Morpho-functional modelling for patient-specific planning in hip arthroplasty (MoFuMo)
Hip endoprostheses are used to treat degenerative hip joint diseases and are the most commonly performed joint replacement procedure worldwide. Preoperative planning of the implantation, taking into account individual morphology based on medical image data, is standard practice. Although the importance of functional parameters such as the resulting hip joint force and sagittal pelvic tilt for the success of the operation has been proven in the literature, these are not routinely taken into account in preoperative planning. This is mainly due to the increased technical effort, time and costs required to estimate these parameters postoperatively.

The project will investigate how accurately the postoperative functional parameters of hip joint strength and pelvic tilt can be predicted in routine clinical practice using preoperative estimates based on morpho-functional models. It will also examine the correlation between these results and postoperative clinical follow-up examinations of treatment outcomes. Hip joint strength will be predicted using statistical modelling of parameterised movement data, replacing the patient-specific movement data previously required for simulation using complex multi-body simulation. A second method will use simplified analytical models to determine hip joint strength for the most important activities of daily living. Both methods will be validated using data from instrumented hip joint implants in the OrthoLoad database. To predict functional pelvic tilt, preoperative and postoperative CT and EOS datasets will be correlated with morphological parameters of the bony pelvis. These modelling approaches will then be integrated into a computer-aided planning system and evaluated using clinical data.
Publications:
- L. Berger, T. Kandels, L. Schmidt-Bleek, K. Tokunaga, P. Damm & K. Radermacher: Modelling of iliopsoas tendon for psoas syndrome evaluation in THA. In: J.W. Giles & A. Guezou-Philippe (ed.): Proceedings of The 24th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, 7, 2024, pp. 16-19 [DOI: 10.29007/rspw]
- L. Berger, A. Stapf, L. Schmidt-Bleek, K. Tokunaga, P. Damm & K. Radermacher: Influence of patient-specific target ROM definition on the combined target zone for cup alignment in THA. In: J.W. Giles & A. Guezou-Philippe (ed.): Proceedings of The 24th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, 7, 2024, pp. 20-24 [DOI: 10.29007/tc34]
- L. Berger, K. Tokunaga & K. Radermacher: Correlation between score values and morphofunctional parameters in THA. In: J.W. Giles (ed.): Proceedings of The 22nd Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, 6, 2024, pp. 1-3 [DOI: 10.29007/zb7x]
- L. Berger, K. Tokunaga & K. Radermacher: Approach towards psoas syndrome risk modeling in preoperative planning for THA. In: J.W. Giles (ed.): Proceedings of The 22nd Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, 6, 2024, pp. 4-7 [DOI: 10.29007/4cld]
- M.C.M. Fischer, S.A.G.A. Grothues, J. Habor, M. de la Fuente & K. Radermacher: A robust method for automatic identification of femoral landmarks, axes, planes and bone coordinate systems using surface models. Scientific Reports, 2020, 10(20859), pp. 1-11 [DOI: 10.1038/s41598-020-77479-z]
- M.C.M. Fischer, K. Tokunaga, M. Okamoto, J. Habor & K. Radermacher: Preoperative factors improving the prediction of the postoperative sagittal orientation of the pelvis in standing position after total hip arthroplasty. Scientific Reports, 2020, 10(15944), pp. 1-10 [DOI: 10.1038/s41598-020-72782-1]
- M.C.M. Fischer, F. Krooß, J. Habor & K. Radermacher: A robust method for automatic identification of landmarks on surface models of the pelvis. Scientific Reports, 2019, 9(13322), pp. 1-10 [DOI: 10.1038/s41598-019-49573-4]
- M.C.M. Fischer, K. Tokunaga, M. Okamoto & K. Radermacher: Proximal Femoral Asymmetry in Japanese Patients before Total Hip Arthroplasty. In: P. Meere & F. Rodriguez Y Baena (ed.): CAOS 2019. The 19th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, 3, 2019, pp. 127-132 [DOI: 10.29007/ms33]
- M.C.M. Fischer, S. Schörner, S. Rohde, C. Lüring & K. Radermacher: Relationship between pelvic morphology and functional parameters in standing position for patient-specific cup planning in THA. In: K. Radermacher & F. Rodriguez Y Baena (ed.): CAOS2017. EPiC Series in Health Sciences, 1, 2017, pp. 88-92 [DOI: 10.29007/41f9]